GHK-Cu

GHK-Cu (Glycyl-L-Histidyl-L-Lysine) is a naturally occurring copper complex that was first isolated from human plasma in 1973. In laboratory settings, this tripeptide has been extensively studied for its high affinity for copper ions, which play a crucial role in various cellular processes. Research indicates that GHK-Cu interacts with DNA and modulates the expression of numerous genes, making it a subject of significant interest in the fields of cellular biology and tissue engineering. Current scientific investigations are focused on understanding the molecular mechanisms by which GHK-Cu influences extracellular matrix remodeling and cellular senescence. In vitro studies frequently utilize this peptide to observe its effects on fibroblast proliferation, collagen synthesis, and the modulation of inflammatory pathways at the cellular level.